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Seneca

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Seneca Flights as Low as $189

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Sep 10 - Sat, Sep 13
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$189 Roundtrip, found 2 days ago
$189
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Sep 10 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Sat, Sep 13, priced at $189 found 2 days ago
United
Wed, Sep 10 - Sat, Sep 13
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$202 Roundtrip, found 2 days ago
$202
Roundtrip
found 2 days ago
Select United flight, departing Wed, Sep 10 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Sat, Sep 13, priced at $202 found 2 days ago
United
Thu, Jul 31 - Thu, Aug 21
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 6 hours ago
$209
Roundtrip
found 6 hours ago
Select United flight, departing Thu, Jul 31 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Thu, Aug 21, priced at $209 found 6 hours ago
Delta
Mon, Sep 8 - Sat, Sep 13
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 2 days ago
$209
Roundtrip
found 2 days ago
Select Delta flight, departing Mon, Sep 8 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Sat, Sep 13, priced at $209 found 2 days ago
American Airlines
Thu, Jul 31 - Thu, Aug 21
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$209 Roundtrip, found 6 hours ago
$209
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Thu, Jul 31 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Thu, Aug 21, priced at $209 found 6 hours ago
Delta
Thu, Jul 31 - Thu, Aug 21
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$222 Roundtrip, found 6 hours ago
$222
Roundtrip
found 6 hours ago
Select Delta flight, departing Thu, Jul 31 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Thu, Aug 21, priced at $222 found 6 hours ago
Delta
Tue, Jul 29 - Tue, Aug 19
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$229 Roundtrip, found 6 hours ago
$229
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Jul 29 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Tue, Aug 19, priced at $229 found 6 hours ago
Delta
Tue, May 20 - Tue, May 27
ECP
Northwest Florida Beaches Intl.
GSP
Greenville-Spartanburg Intl.
$230 Roundtrip, found 4 hours ago
$230
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, May 20 from Northwest Florida Beaches Intl. to Greenville-Spartanburg Intl., returning Tue, May 27, priced at $230 found 4 hours ago
American Airlines
Tue, May 6 - Tue, May 13
DTW
Detroit Metropolitan Wayne County
GSP
Greenville-Spartanburg Intl.
$231 Roundtrip, found 2 days ago
$231
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, May 6 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Tue, May 13, priced at $231 found 2 days ago
Delta
Tue, Apr 22 - Tue, Apr 29
BWI
Baltimore Washington Intl. Thurgood Marshall
GSP
Greenville-Spartanburg Intl.
$256 Roundtrip, found 8 hours ago
$256
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Apr 22 from Baltimore Washington Intl. Thurgood Marshall to Greenville-Spartanburg Intl., returning Tue, Apr 29, priced at $256 found 8 hours ago
Delta
Sat, Apr 12 - Sat, Apr 19
BTR
Baton Rouge Metropolitan
GSP
Greenville-Spartanburg Intl.
$280 Roundtrip, found 1 day ago
$280
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Apr 12 from Baton Rouge Metropolitan to Greenville-Spartanburg Intl., returning Sat, Apr 19, priced at $280 found 1 day ago
American Airlines
Tue, May 6 - Sat, May 10
MHT
Manchester-Boston Regional
GSP
Greenville-Spartanburg Intl.
$284 Roundtrip, found 4 hours ago
$284
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, May 6 from Manchester-Boston Regional to Greenville-Spartanburg Intl., returning Sat, May 10, priced at $284 found 4 hours ago
Delta
Sat, Apr 19 - Sat, Apr 19
RSW
Southwest Florida Intl.
GSP
Greenville-Spartanburg Intl.
$287 Roundtrip, found 9 hours ago
$287
Roundtrip
found 9 hours ago
Select Delta flight, departing Sat, Apr 19 from Southwest Florida Intl. to Greenville-Spartanburg Intl., returning Sat, Apr 19, priced at $287 found 9 hours ago
Delta
Sun, May 25 - Sat, May 31
TLH
Tallahassee Intl.
GSP
Greenville-Spartanburg Intl.
$287 Roundtrip, found 4 hours ago
$287
Roundtrip
found 4 hours ago
Select Delta flight, departing Sun, May 25 from Tallahassee Intl. to Greenville-Spartanburg Intl., returning Sat, May 31, priced at $287 found 4 hours ago
Delta
Sat, Apr 26 - Tue, Apr 29
ONT
Los Angeles - Ontario Intl.
GSP
Greenville-Spartanburg Intl.
$420 Roundtrip, found 11 hours ago
$420
Roundtrip
found 11 hours ago
Select Delta flight, departing Sat, Apr 26 from Los Angeles - Ontario Intl. to Greenville-Spartanburg Intl., returning Tue, Apr 29, priced at $420 found 11 hours ago
Alaska Airlines
Thu, Apr 24 - Mon, Apr 28
ONT
Los Angeles - Ontario Intl.
GSP
Greenville-Spartanburg Intl.
$801 Roundtrip, found 11 hours ago
$801
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Thu, Apr 24 from Los Angeles - Ontario Intl. to Greenville-Spartanburg Intl., returning Mon, Apr 28, priced at $801 found 11 hours ago

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $189, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $189 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$189

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
The price is $134 per night from Apr 9 to Apr 10
$134
includes taxes & fees
Apr 9 - Apr 10
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (832 reviews)
"Great place"

Reviewed on Apr 5, 2025

Lakeside Lodge Clemson
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
The price is $101 per night from Apr 21 to Apr 22
$101
includes taxes & fees
Apr 21 - Apr 22
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (576 reviews)
"Clean and efficient somewhat dated"

Reviewed on Mar 6, 2025

Quality Inn Seneca US-123
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
The price is $128 per night from Apr 13 to Apr 14
$128
includes taxes & fees
Apr 13 - Apr 14
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (693 reviews)
"Rooms are so small, and does not have any closets."

Reviewed on Apr 1, 2025

Tru by Hilton Seneca Clemson
Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
2 out of 5
299 Outpost Rd, Seneca, SC
The price is $110 per night from Apr 9 to Apr 10
$110
includes taxes & fees
Apr 9 - Apr 10
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
10/10 Exceptional! (4 reviews)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"

Reviewed on Feb 16, 2025

Postcard Cabins Lake Hartwell
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 out of 5
511 Bypass Highway 123, Seneca, SC
The price is $98 per night from Apr 14 to Apr 15
$98
includes taxes & fees
Apr 14 - Apr 15
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (579 reviews)
"Very clean rooms, and nice staff."

Reviewed on Mar 28, 2025

Best Western Seneca-Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
The price is $133 per night from Apr 27 to Apr 28
$133
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (587 reviews)
"Very clean and the staff is very helpful"

Reviewed on Mar 12, 2025

Hampton Inn & Suites Seneca-Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
The price is $142 per night from Apr 9 to Apr 10
$142
includes taxes & fees
Apr 9 - Apr 10
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (137 reviews)
"Nice Room , friendly staff , nice and clean breakfast bar!"

Reviewed on Mar 31, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2 out of 5
11015 N Radio Station Rd, Seneca, SC
The price is $76 per night from Apr 13 to Apr 14
$76
includes taxes & fees
Apr 13 - Apr 14
Stay at this motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Applewood ...
6.8/10 (665 reviews)
"Good"

Reviewed on Apr 7, 2025

Days Inn by Wyndham Seneca / Clemson Area
See all 1,547 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.