Search Cheap Flights to
Seneca

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Seneca Flights as Low as $132

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Fri, May 9 - Fri, May 9
BDL
Bradley Intl.
GSP
Greenville-Spartanburg Intl.
$132 Roundtrip, found 5 days ago
$132
Roundtrip
found 5 days ago
Select Breeze Airways flight, departing Fri, May 9 from Bradley Intl. to Greenville-Spartanburg Intl., returning Fri, May 9, priced at $132 found 5 days ago
American Airlines
Tue, Apr 8 - Wed, Apr 9
JFK
John F. Kennedy Intl.
GSP
Greenville-Spartanburg Intl.
$217 Roundtrip, found 22 hours ago
$217
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Apr 8 from John F. Kennedy Intl. to Greenville-Spartanburg Intl., returning Wed, Apr 9, priced at $217 found 22 hours ago
American Airlines
Tue, Mar 25 - Wed, Mar 26
ATL
Hartsfield-Jackson Atlanta Intl.
GSP
Greenville-Spartanburg Intl.
$219 Roundtrip, found 21 hours ago
$219
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Tue, Mar 25 from Hartsfield-Jackson Atlanta Intl. to Greenville-Spartanburg Intl., returning Wed, Mar 26, priced at $219 found 21 hours ago
Delta
Tue, May 6 - Tue, May 13
PVD
T.F. Green
GSP
Greenville-Spartanburg Intl.
$240 Roundtrip, found 1 day ago
$240
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 6 from T.F. Green to Greenville-Spartanburg Intl., returning Tue, May 13, priced at $240 found 1 day ago
Delta
Tue, Apr 15 - Thu, Apr 24
IND
Indianapolis Intl.
GSP
Greenville-Spartanburg Intl.
$247 Roundtrip, found 23 hours ago
$247
Roundtrip
found 23 hours ago
Select Delta flight, departing Tue, Apr 15 from Indianapolis Intl. to Greenville-Spartanburg Intl., returning Thu, Apr 24, priced at $247 found 23 hours ago
American Airlines
Thu, Mar 6 - Thu, Mar 6
CMH
John Glenn Columbus Intl.
GSP
Greenville-Spartanburg Intl.
$260 Roundtrip, found 4 days ago
$260
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Mar 6 from John Glenn Columbus Intl. to Greenville-Spartanburg Intl., returning Thu, Mar 6, priced at $260 found 4 days ago
American Airlines
Wed, Jun 4 - Sat, Jun 7
ROC
Greater Rochester Intl.
GSP
Greenville-Spartanburg Intl.
$280 Roundtrip, found 22 hours ago
$280
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Wed, Jun 4 from Greater Rochester Intl. to Greenville-Spartanburg Intl., returning Sat, Jun 7, priced at $280 found 22 hours ago
Delta
Wed, Apr 2 - Tue, Apr 8
DTW
Detroit Metropolitan Wayne County
GSP
Greenville-Spartanburg Intl.
$283 Roundtrip, found 3 days ago
$283
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Apr 2 from Detroit Metropolitan Wayne County to Greenville-Spartanburg Intl., returning Tue, Apr 8, priced at $283 found 3 days ago
Delta
Tue, May 6 - Tue, May 13
OKC
Will Rogers World
GSP
Greenville-Spartanburg Intl.
$297 Roundtrip, found 1 day ago
$297
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 6 from Will Rogers World to Greenville-Spartanburg Intl., returning Tue, May 13, priced at $297 found 1 day ago
Delta
Mon, Mar 10 - Tue, Mar 11
MCI
Kansas City Intl.
GSP
Greenville-Spartanburg Intl.
$298 Roundtrip, found 1 day ago
$298
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Mar 10 from Kansas City Intl. to Greenville-Spartanburg Intl., returning Tue, Mar 11, priced at $298 found 1 day ago
Delta
Wed, Feb 26 - Mon, Mar 10
MSY
Louis Armstrong New Orleans Intl.
GSP
Greenville-Spartanburg Intl.
$339 Roundtrip, found 1 day ago
$339
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 26 from Louis Armstrong New Orleans Intl. to Greenville-Spartanburg Intl., returning Mon, Mar 10, priced at $339 found 1 day ago
Delta
Mon, May 19 - Wed, May 28
SAN
San Diego Intl.
GSP
Greenville-Spartanburg Intl.
$390 Roundtrip, found 1 day ago
$390
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, May 19 from San Diego Intl. to Greenville-Spartanburg Intl., returning Wed, May 28, priced at $390 found 1 day ago
Delta
Tue, Feb 25 - Mon, Mar 3
MCO
Orlando Intl.
GSP
Greenville-Spartanburg Intl.
$468 Roundtrip, found 1 day ago
$468
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Feb 25 from Orlando Intl. to Greenville-Spartanburg Intl., returning Mon, Mar 3, priced at $468 found 1 day ago
American Airlines
Mon, Feb 24 - Mon, Mar 3
JAN
Evers Intl.
GSP
Greenville-Spartanburg Intl.
$477 Roundtrip, found 1 day ago
$477
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Feb 24 from Evers Intl. to Greenville-Spartanburg Intl., returning Mon, Mar 3, priced at $477 found 1 day ago
Delta
Mon, Feb 24 - Mon, Mar 3
MOB
Mobile Regional
GSP
Greenville-Spartanburg Intl.
$512 Roundtrip, found 1 day ago
$512
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Feb 24 from Mobile Regional to Greenville-Spartanburg Intl., returning Mon, Mar 3, priced at $512 found 1 day ago
Copa
Wed, Mar 12 - Sat, Apr 5
CLO
Alfonso Bonilla Aragon Intl.
GSP
Greenville-Spartanburg Intl.
$589 Roundtrip, found 1 day ago
$589
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Mar 12 from Alfonso Bonilla Aragon Intl. to Greenville-Spartanburg Intl., returning Sat, Apr 5, priced at $589 found 1 day ago

Cheap Flights to Seneca

Fall in love at first flight with your vacation to Seneca by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Seneca on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Seneca, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Seneca

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Seneca with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GSP airport.

What is the cheapest month to fly to Seneca?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Seneca are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Seneca?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Seneca.

What airport is best to fly into Seneca?

When you’re planning your trip to Seneca, convenience is the name of the game. Luckily, Seneca Greenville-Spartanburg Intl. Airport is nearby so you can deplane and get going on checking off everything on your Seneca must-do list.

How much are flights to Seneca?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Seneca on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $132, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Seneca?

The trick to saving a stack of cash on your flight to Seneca? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $132 right now, why wait?

Seneca Flight Information
Destination airport
Greenville-Spartanburg Intl.
Destination airport IATA code
GSP
Roundtrip price
$131

Last Minute Hotel Deals in Seneca

Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
The price is $134 per night from Feb 19 to Feb 20
$134
includes taxes & fees
Feb 19 - Feb 20
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (790 reviews)
"Extremely impressed! Very clean and very spacious!! Such friendly staff as well!"

Reviewed on Feb 17, 2025

Lakeside Lodge Clemson
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
The price is $139 per night from Feb 23 to Feb 24
$139
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (577 reviews)
"Nice & efficient staff"

Reviewed on Feb 2, 2025

Hampton Inn & Suites Seneca-Clemson Area
Postcard Cabins Lake Hartwell
Postcard Cabins Lake Hartwell
2 out of 5
299 Outpost Rd, Seneca, SC
The price is $83 per night from Mar 4 to Mar 5
$83
includes taxes & fees
Mar 4 - Mar 5
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
10/10 Exceptional! (3 reviews)
"This is a fantastic place to stay and get away. Good for quiet work or true relaxation. Internet was blazing fast too. Can I stay forever?"

Reviewed on Feb 16, 2025

Postcard Cabins Lake Hartwell
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
The price is $127 per night from Mar 4 to Mar 5
$127
includes taxes & fees
Mar 4 - Mar 5
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (672 reviews)
"Check in clerk was awesome. Very friendly and helpful."

Reviewed on Feb 10, 2025

Tru by Hilton Seneca Clemson
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
The price is $142 per night from Feb 19 to Feb 20
$142
includes taxes & fees
Feb 19 - Feb 20
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (132 reviews)
"Very nice hotel !"

Reviewed on Jan 18, 2025

Fairfield Inn & Suites Seneca Clemson Univ Area
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 out of 5
511 Bypass Highway 123, Seneca, SC
The price is $107 per night from Feb 26 to Feb 27
$107
includes taxes & fees
Feb 26 - Feb 27
Book a stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (572 reviews)
"It was very peaceful and the staff was very nice."

Reviewed on Feb 16, 2025

Best Western Seneca-Clemson
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
The price is $199 per night from Mar 16 to Mar 17
$199
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (491 reviews)
"Amazing place! Love what you do"

Reviewed on Feb 18, 2025

The Shepherd Hotel Downtown Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
The price is $112 per night from Feb 23 to Feb 24
$112
includes taxes & fees
Feb 23 - Feb 24
Book a stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,002 reviews)
"There was a bug on the shower wall… But I was glad to get a shower after our long trip…"

Reviewed on Feb 15, 2025

Best Western Plus Clemson Hotel & Conference Center
See all 1,525 properties in Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.