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Southwest Illinois

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Southwest Illinois Flights as Low as $79

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Wed, Apr 9 - Thu, Apr 10
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$79 Roundtrip, found 1 day ago
$79
Roundtrip
found 1 day ago
Select United flight, departing Wed, Apr 9 from O'Hare Intl. to Lambert-St. Louis Intl., returning Thu, Apr 10, priced at $79 found 1 day ago
American Airlines
Wed, Apr 9 - Thu, Apr 10
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$86 Roundtrip, found 1 day ago
$86
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 9 from O'Hare Intl. to Lambert-St. Louis Intl., returning Thu, Apr 10, priced at $86 found 1 day ago
American Airlines
Wed, Apr 9 - Thu, Apr 10
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$91 Roundtrip, found 1 day ago
$91
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 9 from O'Hare Intl. to Lambert-St. Louis Intl., returning Thu, Apr 10, priced at $91 found 1 day ago
United
Wed, Apr 9 - Thu, Apr 10
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$96 Roundtrip, found 1 day ago
$96
Roundtrip
found 1 day ago
Select United flight, departing Wed, Apr 9 from O'Hare Intl. to Lambert-St. Louis Intl., returning Thu, Apr 10, priced at $96 found 1 day ago
United
Wed, Apr 9 - Thu, Apr 10
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$111 Roundtrip, found 1 day ago
$111
Roundtrip
found 1 day ago
Select United flight, departing Wed, Apr 9 from O'Hare Intl. to Lambert-St. Louis Intl., returning Thu, Apr 10, priced at $111 found 1 day ago
Southern Airways Express
Mon, Apr 7 - Sun, Apr 13
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$116 Roundtrip, found 1 day ago
$116
Roundtrip
found 1 day ago
Select Southern Airways Express flight, departing Mon, Apr 7 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sun, Apr 13, priced at $116 found 1 day ago
American Airlines
Wed, Apr 9 - Thu, Apr 10
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$117 Roundtrip, found 1 day ago
$117
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Apr 9 from O'Hare Intl. to Lambert-St. Louis Intl., returning Thu, Apr 10, priced at $117 found 1 day ago
American Airlines
Thu, Apr 24 - Sat, Apr 26
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$119 Roundtrip, found 4 days ago
$119
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 24 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sat, Apr 26, priced at $119 found 4 days ago
United
Thu, Apr 24 - Sat, Apr 26
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$121 Roundtrip, found 4 days ago
$121
Roundtrip
found 4 days ago
Select United flight, departing Thu, Apr 24 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sat, Apr 26, priced at $121 found 4 days ago
American Airlines
Thu, Apr 24 - Sat, Apr 26
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$121 Roundtrip, found 4 days ago
$121
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 24 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sat, Apr 26, priced at $121 found 4 days ago
Frontier Airlines
Tue, Apr 22 - Wed, Apr 23
SFO
San Francisco Intl.
STL
Lambert-St. Louis Intl.
$160 Roundtrip, found 3 days ago
$160
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Apr 22 from San Francisco Intl. to Lambert-St. Louis Intl., returning Wed, Apr 23, priced at $160 found 3 days ago
Frontier Airlines
Wed, Apr 2 - Wed, Apr 9
ONT
Los Angeles - Ontario Intl.
STL
Lambert-St. Louis Intl.
$161 Roundtrip, found 3 days ago
$161
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Apr 2 from Los Angeles - Ontario Intl. to Lambert-St. Louis Intl., returning Wed, Apr 9, priced at $161 found 3 days ago
Delta
Thu, Apr 24 - Sat, Apr 26
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$177 Roundtrip, found 4 days ago
$177
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Apr 24 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sat, Apr 26, priced at $177 found 4 days ago
Frontier Airlines
Sun, Mar 16 - Wed, Mar 26
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$287 Roundtrip, found 1 day ago
$287
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Mar 16 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Wed, Mar 26, priced at $287 found 1 day ago
Alaska Airlines
Thu, Apr 3 - Tue, Apr 8
ONT
Los Angeles - Ontario Intl.
STL
Lambert-St. Louis Intl.
$395 Roundtrip, found 3 days ago
$395
Roundtrip
found 3 days ago
Select Alaska Airlines flight, departing Thu, Apr 3 from Los Angeles - Ontario Intl. to Lambert-St. Louis Intl., returning Tue, Apr 8, priced at $395 found 3 days ago
Hawaiian Airlines
Tue, Apr 22 - Fri, Apr 25
SFO
San Francisco Intl.
STL
Lambert-St. Louis Intl.
$470 Roundtrip, found 2 days ago
$470
Roundtrip
found 2 days ago
Select Hawaiian Airlines flight, departing Tue, Apr 22 from San Francisco Intl. to Lambert-St. Louis Intl., returning Fri, Apr 25, priced at $470 found 2 days ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $79, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $79 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$79

Last Minute Hotel Deals in Southwest Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
The price is $117 per night from Apr 6 to Apr 7
$117
includes taxes & fees
Apr 6 - Apr 7
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,246 reviews)
"Included food excellent, very nice hotel"

Reviewed on Mar 12, 2025

Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
The price is $57 per night from Mar 19 to Mar 20
$57
includes taxes & fees
Mar 19 - Mar 20
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,000 reviews)
"Nice big bed with lots of pillows, good shower pressure and a quiet nite except for the fridge which I had to unplug to sleep"

Reviewed on Mar 7, 2025

Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
The price is $130 per night from Mar 18 to Mar 19
$130
includes taxes & fees
Mar 18 - Mar 19
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,019 reviews)
Lovely place to stay
"It was amazing Great food great people"

Reviewed on Mar 10, 2025

Drury Inn & Suites St. Louis O'Fallon, IL
Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach
2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
The price is $67 per night from Mar 18 to Mar 19
$67
includes taxes & fees
Mar 18 - Mar 19
Stay at this hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (286 reviews)
"Clean and comfortable"

Reviewed on Mar 7, 2025

Red Lion Inn & Suites Pontoon Beach
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
The price is $128 per night from Apr 1 to Apr 2
$128
includes taxes & fees
Apr 1 - Apr 2
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,000 reviews)
"Friendly staff, excellent customer service! I always enjoy the breakfast buffet and the evening "Kick-Back""

Reviewed on Mar 10, 2025

Drury Inn & Suites St. Louis Fairview Heights
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
The price is $144 per night from Mar 16 to Mar 17
$144
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4.5-star luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (292 reviews)
"Very friendly staff and clean."

Reviewed on Mar 10, 2025

Walker's Bluff Casino Resort
Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 out of 5
2608 W Main St, Marion, IL
The price is $97 per night from Mar 16 to Mar 17
$97
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,000 reviews)
"Great experience."

Reviewed on Mar 10, 2025

Baymont by Wyndham Marion
Red Lion Inn & Suites Caseyville
Red Lion Inn & Suites Caseyville
2 out of 5
8950 Tucker Dr, Caseyville, IL
The price is $60 per night from Mar 18 to Mar 19
$60
includes taxes & fees
Mar 18 - Mar 19
Stay at this motel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia Mounds State Historic ...
5.4/10 (180 reviews)
Stay Here
"Very friendly staff they make you feel right at home."

Reviewed on Mar 4, 2025

Red Lion Inn & Suites Caseyville
See all 637 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.