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Southwest Illinois

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Southwest Illinois Flights as Low as $121

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Feb 15 - Mon, Feb 24
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$121 Roundtrip, found 2 days ago
$121
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Feb 15 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Mon, Feb 24, priced at $121 found 2 days ago
Frontier Airlines
Sat, Feb 15 - Sun, Feb 16
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$122 Roundtrip, found 2 days ago
$122
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Feb 15 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sun, Feb 16, priced at $122 found 2 days ago
Frontier Airlines
Fri, Feb 14 - Sun, Feb 16
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$124 Roundtrip, found 2 days ago
$124
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Feb 14 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sun, Feb 16, priced at $124 found 2 days ago
Frontier Airlines
Tue, Jan 14 - Sat, Jan 18
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$128 Roundtrip, found 4 days ago
$128
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Tue, Jan 14 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Sat, Jan 18, priced at $128 found 4 days ago
Frontier Airlines
Sat, Feb 22 - Mon, Feb 24
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$130 Roundtrip, found 1 day ago
$130
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Feb 22 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Mon, Feb 24, priced at $130 found 1 day ago
Frontier Airlines
Fri, Feb 14 - Tue, Feb 18
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$131 Roundtrip, found 2 days ago
$131
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Fri, Feb 14 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Tue, Feb 18, priced at $131 found 2 days ago
Frontier Airlines
Sun, Jan 19 - Wed, Jan 22
HOU
William P. Hobby
STL
Lambert-St. Louis Intl.
$270 Roundtrip, found 1 day ago
$270
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Jan 19 from William P. Hobby to Lambert-St. Louis Intl., returning Wed, Jan 22, priced at $270 found 1 day ago
Delta
Wed, Feb 19 - Wed, Feb 19
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$271 Roundtrip, found 1 day ago
$271
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Feb 19 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Wed, Feb 19, priced at $271 found 1 day ago
Spirit Airlines
Thu, Jan 16 - Thu, Jan 30
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$276 Roundtrip, found 1 day ago
$276
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Jan 16 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Thu, Jan 30, priced at $276 found 1 day ago
United
Wed, Feb 19 - Sat, Feb 22
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$277 Roundtrip, found 22 hours ago
$277
Roundtrip
found 22 hours ago
Select United flight, departing Wed, Feb 19 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sat, Feb 22, priced at $277 found 22 hours ago
American Airlines
Wed, Feb 19 - Sat, Feb 22
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$277 Roundtrip, found 22 hours ago
$277
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Wed, Feb 19 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sat, Feb 22, priced at $277 found 22 hours ago
Alaska Airlines
Wed, Feb 19 - Sat, Feb 22
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$400 Roundtrip, found 22 hours ago
$400
Roundtrip
found 22 hours ago
Select Alaska Airlines flight, departing Wed, Feb 19 from Harry Reid Intl. to Lambert-St. Louis Intl., returning Sat, Feb 22, priced at $400 found 22 hours ago
Delta
Tue, Feb 25 - Wed, Mar 5
YUL
Pierre Elliott Trudeau Intl.
STL
Lambert-St. Louis Intl.
$435 Roundtrip, found 1 day ago
$435
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Feb 25 from Pierre Elliott Trudeau Intl. to Lambert-St. Louis Intl., returning Wed, Mar 5, priced at $435 found 1 day ago
Air Canada
Sat, Mar 1 - Thu, Mar 6
YUL
Pierre Elliott Trudeau Intl.
STL
Lambert-St. Louis Intl.
$544 Roundtrip, found 1 day ago
$544
Roundtrip
found 1 day ago
Select Air Canada flight, departing Sat, Mar 1 from Pierre Elliott Trudeau Intl. to Lambert-St. Louis Intl., returning Thu, Mar 6, priced at $544 found 1 day ago
American Airlines
Sun, Jan 26 - Tue, Jan 28
IAH
George Bush Intercontinental
PAH
Barkley Regional
$634 Roundtrip, found 6 days ago
$634
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Jan 26 from George Bush Intercontinental to Barkley Regional, returning Tue, Jan 28, priced at $634 found 6 days ago
WestJet
Fri, Feb 28 - Thu, Mar 6
YUL
Pierre Elliott Trudeau Intl.
STL
Lambert-St. Louis Intl.
$666 Roundtrip, found 1 day ago
$666
Roundtrip
found 1 day ago
Select WestJet flight, departing Fri, Feb 28 from Pierre Elliott Trudeau Intl. to Lambert-St. Louis Intl., returning Thu, Mar 6, priced at $666 found 1 day ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $121, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $121 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$120

Last Minute Hotel Deals in Southwest Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
The price is $127 per night from Jan 19 to Jan 20
$127
includes taxes & fees
Jan 19 - Jan 20
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,204 reviews)
"I loved that their breakfast was more than a continental one. I also love that dinner is served and is free, and the newly added restaurant is a bonus I ate there and the food was very good and the service was amazing. 10 stars!"

Reviewed on Jan 9, 2025

Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
The price is $120 per night from Jan 15 to Jan 16
$120
includes taxes & fees
Jan 15 - Jan 16
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
"Friendly staff, good food and clean room. One elevator was out and it was busy but overall good stay"

Reviewed on Jan 11, 2025

Drury Inn & Suites St. Louis O'Fallon, IL
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
The price is $57 per night from Jan 19 to Jan 20
$57
includes taxes & fees
Jan 19 - Jan 20
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,003 reviews)
"It was good"

Reviewed on Dec 29, 2024

Super 8 by Wyndham O'Fallon
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
The price is $144 per night from Jan 12 to Jan 13
$144
includes taxes & fees
Jan 12 - Jan 13
Stay at this 4.5-star luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (266 reviews)
"It was really nice rooms"

Reviewed on Dec 27, 2024

Walker's Bluff Casino Resort
Drury Inn & Suites Marion
Drury Inn & Suites Marion
3 out of 5
2706 W DeYoung St, Marion, IL
The price is $132 per night from Jan 12 to Jan 13
$132
includes taxes & fees
Jan 12 - Jan 13
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
"We loved the meal and drinks that were free with our stay! The beds are comfy but the room is a little small. We would stay here again!"

Reviewed on Jan 9, 2025

Drury Inn & Suites Marion
DoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Mt. Vernon
4 out of 5
222 Potomac Blvd, Mount Vernon, IL
The price is $125 per night from Jan 25 to Jan 26
$125
includes taxes & fees
Jan 25 - Jan 26
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the ...
8.2/10 Very Good! (628 reviews)
"As a traveler, this place was convenient & nice play to stay."

Reviewed on Jan 4, 2025

DoubleTree by Hilton Mt. Vernon
Super 8 by Wyndham Marion
Super 8 by Wyndham Marion
2 out of 5
2601 Vernell Rd, Marion, IL
The price is $75 per night from Jan 17 to Jan 18
$75
includes taxes & fees
Jan 17 - Jan 18
Book a stay at this business-friendly motel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,000 reviews)
Good
"Good for an overnight"

Reviewed on Dec 29, 2024

Super 8 by Wyndham Marion
Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 out of 5
2608 W Main St, Marion, IL
The price is $86 per night from Jan 12 to Jan 13
$86
includes taxes & fees
Jan 12 - Jan 13
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,003 reviews)
"We were looking for a nice quiet stop over Christmas and this hotel fit the bill."

Reviewed on Jan 3, 2025

Baymont by Wyndham Marion
See all 651 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.