Adults Only Resorts & Hotels in
Panama City


Featured Panama City Adults Only Resorts & Hotels

Hostel Danicole
Hostel Danicole
2 out of 5
Ave 8va Norte Duplex 2, Urbanizacion Los Angeles, Panama City
Hostel Danicole
Niceplace Inn
Niceplace Inn
3 out of 5
Casco Viejo Panama, Calle 4 Este, Con Avenida B, Panama City
Niceplace Inn
Tantalo Hotel
Tantalo Hotel
3.5 out of 5
Calle 8 Este con Avenida B, Casco Viejo, San Felipe, Ciudad de Panama, Panama City, Panama
The price is $100 per night from Nov 24 to Nov 25
$100
includes taxes & fees
Nov 24 - Nov 25
Tantalo Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Panama City

Panamá Province is a city that has a lot going on, but you have your sights set on Panama City. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Panama City has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Panama City hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Panamá Province so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Panama City underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Panama City city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Panama City cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Panama City at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $100
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Panama City hotel you want, book it, and never look back. Because your great escape is ahead of you.