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Featured Luxury Southeast Missouri
Super 8 by Wyndham Pevely
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Comfort Inn Festus - St Louis South
1303 Veterans Blvd, Festus, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Super 8 by Wyndham Poplar Bluff Missouri
2831 N Westwood Blvd, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Margaret Harwell Art Museum ...
Quality Inn Festus
1200 W Gannon Dr, Festus, MO
Stay at this 3-star family-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jorkerst Memorial Park and Sunset ...
Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Southeast Missouri
- Hotels with Free Parking in Southeast Missouri
- Family Hotels in Southeast Missouri
- Pet-friendly Hotels in Southeast Missouri
- Hotels with a Pool in Southeast Missouri
- Hotels with an Indoor Pool in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotel Wedding Venues in Southeast Missouri
- Resorts & Hotels with Spas in Southeast Missouri
- Casinos in Southeast Missouri
- Apartment Hotel in Southeast Missouri
Southeast Missouri Neighborhoods
Top Points of Interests in Southeast Missouri
- Hotels near Elephant Rocks State Park
- Hotels near Southeast Missouri State University
- Hotels near Ozark National Scenic Riverways
- Hotels near Isle Casino Cape Girardeau
- Hotels near Lake Wappapello
- Hotels near Johnson's Shut-ins State Park
- Hotels near Century Casino Caruthersville
- Hotels near Echo Bluff State Park
- Hotels near Big Spring
- Hotels near Taum Sauk Mountain State Park
- Hotels near Sainte Genevieve Winery
- Hotels near The Book Bug
- Hotels near Black River Coliseum
- Hotels near Riverfront Park
- Hotels near Bonne Terre Mine
- Hotels near St. Francois State Park
- Hotels near Big River
- Hotels near Current River State Park
- Hotels near National Shrine of Our Lady of the Miraculous Medal
Cities near Southeast Missouri
- Ste Genevieve Hotels (56.1 mi)
- Cape Girardeau Hotels (50.24 mi)
- Chesterfield Hotels (99.53 mi)
- Carbondale Hotels (74.86 mi)
- Poplar Bluff Hotels (32.28 mi)
- Ozarks Hotels (113.87 mi)
- Sikeston Hotels (51.94 mi)
- Farmington Hotels (38.48 mi)
- Fenton Hotels (89.01 mi)
- Wildwood Hotels (94.69 mi)
- Kirkwood Hotels (93.89 mi)
- Richmond Heights Hotels (97.19 mi)
- Southern Illinois Hotels (119.89 mi)
- Anna Hotels (66.78 mi)
- Eminence Hotels (51.47 mi)
- Eureka Hotels (88.99 mi)
- Arnold Hotels (83.54 mi)
- Dyersburg Hotels (100.34 mi)
- Blytheville Hotels (94.02 mi)
- Ballwin Hotels (94.92 mi)
Car Rentals Near Southeast Missouri
- Car rentals in Ste Genevieve
- Car rentals in Cape Girardeau
- Car rentals in Chesterfield
- Car rentals in Carbondale
- Car rentals in Poplar Bluff
- Car rentals in Ozarks
- Car rentals in Sikeston
- Car rentals in Farmington
- Car rentals in Fenton
- Car rentals in Wildwood
- Car rentals in Kirkwood
- Car rentals in Richmond Heights
- Car rentals in Southern Illinois
- Car rentals in Anna
- Car rentals in Eminence
- Car rentals in Eureka
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