Hotels Near
Texas Medical Center

Check Last Minute Texas Medical Center Hotel Deals

Tonight Feb 2 - Feb 3Next weekend Feb 7 - Feb 9

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking!


Featured Texas Medical Center Hotels

Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,085 reviews)
"It my go to hotel in HOUSTON"

Reviewed on Jan 28, 2025

Blossom Hotel Houston
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical Center
3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,392 reviews)
"Very clean, super comfy beds, great shower. Maid service was sub par."

Reviewed on Jan 30, 2025

Hyatt Place Houston Medical Center
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
3.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,167 reviews)
"."

Reviewed on Jan 27, 2025

Hilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & Suites
4 out of 5
6800 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (263 reviews)
"Great place to stay but you have to pay for internet"

Reviewed on Jan 29, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Hyatt House Houston Medical Center
Hyatt House Houston Medical Center
3 out of 5
7329 FANNIN STREET, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (863 reviews)
"Nice"

Reviewed on Jan 30, 2025

Hyatt House Houston Medical Center
InterContinental Houston, an IHG Hotel
InterContinental Houston, an IHG Hotel
4 out of 5
6750 Main St, Houston, TX
Fully refundable
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,003 reviews)
Luxury stay in Houston
"The room and hotel were very clean, front desk clerk was very helpful service was excellent, food was excellent"

Reviewed on Jan 30, 2025

InterContinental Houston, an IHG Hotel
Hampton Inn & Suites Houston Medical Center NRG Park
Hampton Inn & Suites Houston Medical Center NRG Park
2.5 out of 5
1715 Old Spanish Trl, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our ...
8.2/10 Very Good! (1,002 reviews)
"Great hotel with free breakfast and free shuttle service. Staff was always friendly and helpful."

Reviewed on Jan 25, 2025

Hampton Inn & Suites Houston Medical Center NRG Park
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District
4 out of 5
1709 DRYDEN ROAD, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour health club. Our guests praise the helpful ...
9/10 Wonderful! (1,000 reviews)
"So convenient if you’re an MDA patient. Staff is very friendly and I felt safe when navigating the area. Security guards presence in the area was comforting. Property very clean and beds super comfortable."

Reviewed on Jan 28, 2025

The Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum District
4 out of 5
6580 Fannin Street, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,000 reviews)
"Walkable to Houston Methodist Hospital."

Reviewed on Jan 23, 2025

Houston Marriott Medical Center/Museum District
Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TX
3 out of 5
6840 Almeda Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
9.2/10 Wonderful! (700 reviews)
"Like the garage parking very private"

Reviewed on Jan 28, 2025

Hilton Garden Inn Houston Medical Center, TX
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,725 reviews)
"Employees go above and beyond Friendly staff"

Reviewed on Jan 26, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hyatt Place Houston-North
Hyatt Place Houston-North
3.5 out of 5
300 Ronan Park Place, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
6.6/10 (833 reviews)
"Every thing was nice and clean"

Reviewed on Jan 30, 2025

Hyatt Place Houston-North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Texas Medical Center

Houston is a city that has a lot going on, but you have your sights set on Texas Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Texas Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Texas Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Houston so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Texas Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Texas Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Texas Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Texas Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $86
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Texas Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.