Hotels Near
Texas Medical Center

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Featured Texas Medical Center Hotels

Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
3.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, an outdoor pool, and a rooftop terrace. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,295 reviews)
"Location and cleaniness."

Reviewed on Apr 27, 2025

Hilton Houston Plaza/Medical Center
Blossom Hotel Houston
Blossom Hotel Houston
4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star spa hotel in Houston. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (3,268 reviews)
"While this property does not have much around it, it is beautiful inside and the rooms are new and comfortable. Bed was great and the rooftop pool clean!"

Reviewed on Apr 26, 2025

Blossom Hotel Houston
Hyatt Place Houston Medical Center
Hyatt Place Houston Medical Center
3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (1,581 reviews)
"Nice hotel. My room showed signs of age for a new hotel. Paint chipped"

Reviewed on Apr 25, 2025

Hyatt Place Houston Medical Center
Hampton Inn & Suites Houston Medical Center NRG Park
Hampton Inn & Suites Houston Medical Center NRG Park
2.5 out of 5
1715 Old Spanish Trl, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our ...
8.2/10 Very Good! (1,009 reviews)
"Great place. Clean and comfortable!"

Reviewed on Apr 27, 2025

Hampton Inn & Suites Houston Medical Center NRG Park
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & Suites
4 out of 5
6800 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (313 reviews)
"83257-0012-33"

Reviewed on Apr 24, 2025

DoubleTree by Hilton Houston Medical Center Hotel & Suites
Hilton Garden Inn Houston Medical Center, TX
Hilton Garden Inn Houston Medical Center, TX
3 out of 5
6840 Almeda Rd, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
9.2/10 Wonderful! (800 reviews)
"The hotel was very clean. Everyone was accommodating and friendly, especially the ladies in the breakfast area who were exceptional."

Reviewed on Apr 24, 2025

Hilton Garden Inn Houston Medical Center, TX
InterContinental Houston by IHG
InterContinental Houston by IHG
4 out of 5
6750 Main St, Houston, TX
Fully refundable
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,001 reviews)
"Great place to stay while in Houston! Needed to be close to Rice University and this was perfect!"

Reviewed on Apr 26, 2025

InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum District
4 out of 5
1709 DRYDEN ROAD, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9/10 Wonderful! (1,000 reviews)
"Staff was very freindly and accomadating."

Reviewed on Apr 21, 2025

The Westin Houston Medical Center/Museum District
Hyatt House Houston Medical Center
Hyatt House Houston Medical Center
3 out of 5
7329 FANNIN STREET, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (951 reviews)
"It was a great experience. The staff was very friendly."

Reviewed on Apr 25, 2025

Hyatt House Houston Medical Center
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum District
4 out of 5
6580 Fannin Street, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,003 reviews)
"Staff was very accommodating and helpful"

Reviewed on Apr 24, 2025

Houston Marriott Medical Center/Museum District
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4 out of 5
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,266 reviews)
"Loved the location! Right in the heart of downtown Houston. Near so many walkable activities!!"

Reviewed on Apr 25, 2025

Club Quarters Hotel Downtown, Houston
Sonesta Hotel Houston IAH Airport
Sonesta Hotel Houston IAH Airport
4 out of 5
425 North Sam Houston Parkway East, Houston, TX
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
7.4/10 Good! (1,004 reviews)
"Clean environment, friendly staff"

Reviewed on Apr 15, 2025

Sonesta Hotel Houston IAH Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Texas Medical Center

Houston is a city that has a lot going on, but you have your sights set on Texas Medical Center. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Texas Medical Center has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Texas Medical Center hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Houston so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Texas Medical Center underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Texas Medical Center city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Texas Medical Center cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Texas Medical Center at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $112
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Texas Medical Center hotel you want, book it, and never look back. Because your great escape is ahead of you.