Search for Cheap Deals on4 Star Hotels in Clayton
Check Last Minute Clayton Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured 4 Star Clayton Hotels
Fully refundableReserve now, pay when you stay
The price is $126 per night from Jan 6 to Jan 7
$126
includes taxes & fees
Jan 6 - Jan 7
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Fully refundableReserve now, pay when you stay
The price is $133 per night from Jan 24 to Jan 25
$133
includes taxes & fees
Jan 24 - Jan 25
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Fully refundableReserve now, pay when you stay
The price is $170 per night from Jan 2 to Jan 3
$170
includes taxes & fees
Jan 2 - Jan 3
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Save an average of 15% on thousands of hotels when you're signed in
Fully refundableReserve now, pay when you stay
The price is $189 per night from Jan 2 to Jan 3
$189
includes taxes & fees
Jan 2 - Jan 3
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Fully refundableReserve now, pay when you stay
The price is $214 per night from Jan 2 to Jan 3
$214
includes taxes & fees
Jan 2 - Jan 3
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Fully refundableReserve now, pay when you stay
The price is $117 per night from Jan 20 to Jan 21
$117
includes taxes & fees
Jan 20 - Jan 21
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Fully refundableReserve now, pay when you stay
The price is $145 per night from Jan 3 to Jan 4
$145
includes taxes & fees
Jan 3 - Jan 4
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
Fully refundableReserve now, pay when you stay
The price is $114 per night from Jan 12 to Jan 13
$114
includes taxes & fees
Jan 12 - Jan 13
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
Fully refundableReserve now, pay when you stay
The price is $189 per night from Jan 2 to Jan 3
$189
includes taxes & fees
Jan 2 - Jan 3
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Fully refundableReserve now, pay when you stay
The price is $187 per night from Jan 4 to Jan 5
$187
includes taxes & fees
Jan 4 - Jan 5
Book a stay at this eco-certified hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Fully refundableReserve now, pay when you stay
The price is $189 per night from Jan 5 to Jan 6
$189
includes taxes & fees
Jan 5 - Jan 6
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
Fully refundableReserve now, pay when you stay
The price is $122 per night from Jan 10 to Jan 11
$122
includes taxes & fees
Jan 10 - Jan 11
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), a fitness center, and valet parking (surcharge). Our guests praise the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Hotel Options in Clayton
- Historic Hotels in Clayton
- Family Hotels in Clayton
- Hotels with a Pool in Clayton
- Hotel Wedding Venues in Clayton
- Hotels with Hot Tubs in Clayton
- Romantic Hotels in Clayton
- Luxury Hotels in Clayton
- Boutique Hotels in Clayton
- Resorts & Hotels with Spas in Clayton
- Hotels with an Indoor Pool in Clayton
Popular Clayton Hotels
- Clayton Plaza Hotel & Extended Stay
- Le Méridien St. Louis Clayton
- The Ritz-Carlton, St. Louis
- Homewood Suites by Hilton St Louis - Galleria
- Hampton Inn & Suites Clayton/St. Louis-Galleria Area
- Hyatt Regency St. Louis at The Arch
- Hollywood Casino & Hotel St. Louis
- The Last Hotel
- Renaissance St. Louis Airport Hotel
Top Attractions in Clayton
- Hotels near Chapel of St. Timothy And St. Titus (0.71 mi)
- Hotels near St. Louis Union Station (6.35 mi)
- Hotels near Gateway Arch (7.59 mi)
- Hotels near Enterprise Center (6.62 mi)
- Hotels near St. Louis Zoo (1.86 mi)
- Hotels near Busch Stadium (7.18 mi)
- Hotels near Washington University in St. Louis (0.84 mi)
- Hotels near Dome at America’s Center (7.31 mi)
- Hotels near City Museum (6.66 mi)
- Hotels near Ameristar Casino St. Charles (12.3 mi)
- Hotels near Forest Park (2.49 mi)
- Hotels near St. Louis University (4.93 mi)
- Hotels near America's Center Convention Complex (7.18 mi)
- Hotels near Barnes Jewish Hospital (3.21 mi)
- Hotels near Mississippi River (76.74 mi)
- Hotels near Hollywood Casino Amphitheatre (10.51 mi)
- Hotels near Fox Theater (4.96 mi)
- Hotels near St Charles Convention Center (12.99 mi)
- Hotels near Missouri Botanical Gardens and Arboretum (4.03 mi)
- Hotels near Horseshoe St. Louis Casino (7.55 mi)
Nearby Cities
- St. Charles Hotels (13.73 mi)
- Maryland Heights Hotels (7.51 mi)
- Bridgeton Hotels (9.81 mi)
- Chesterfield Hotels (13.04 mi)
- Hazelwood Hotels (10.12 mi)
- O'Fallon Hotels (22.54 mi)
- St. Ann Hotels (7.04 mi)
- O'Fallon Hotels (23.35 mi)
- St. Peters Hotels (19 mi)
- Collinsville Hotels (18.31 mi)
- Ozarks Hotels (156.82 mi)
- Fairview Heights Hotels (17.13 mi)
Recommended cities for you
- Las Vegas Hotels
- New York Hotels
- Orlando Hotels
- Los Angeles Hotels
- Miami Hotels
- San Francisco Hotels
- New Orleans Hotels
- Chicago Hotels
- Fort Lauderdale Hotels
- Boston Hotels
- Honolulu Hotels
- San Diego Hotels
- Washington Hotels
- Toronto Hotels
- Anaheim Hotels
- Atlanta Hotels
- Nashville Hotels
- Seattle Hotels
- Phoenix Hotels
- Myrtle Beach Hotels
Car Rentals Near Clayton
- Car rentals in St. Charles
- Car rentals in Maryland Heights
- Car rentals in Bridgeton
- Car rentals in Chesterfield
- Car rentals in Hazelwood
- Car rentals in O'Fallon
- Car rentals in St. Ann
- Car rentals in O'Fallon
- Car rentals in St. Peters
- Car rentals in Collinsville
- Car rentals in Ozarks
- Car rentals in Fairview Heights
- Car rentals in Edwardsville
- Car rentals in Fenton
- Car rentals in Alton
- Car rentals in Kirkwood